Peter Parker struggles to balance the best summer vacation ever and his responsibilities as Spider-Man.

Spider-Man is excited to start his second year as a superhero and as a student at Horizon High, but discovers that Doc Ock also claims to want a second chance.

Spider-Man discovers there is a new Doctor Octopus taking up the mantle from Otto Octavius and finds himself drawn into this new mystery, missing the danger right under his nose.

Spider-Man has to infiltrate the viral superstars known as the Wake Riders in order to figure out what the end game is with their stolen Vulture tech. But things take a dangerous turn as Adrian Toomes is tempted back to the dark side.

Spider-Man teams up with Ms. Marvel to investigate an elite boarding school after its students start displaying out-of-control, super-powered behaviors.

Eddie Brock, who has emerged with the vengeance-filled Venom symbiote, sets his sights on destroying Peter Parker and everything that is Spider-Man.

Spider-Man is two steps behind as Venom kidnaps key figures in Peter Parker's life; demanding a face-off against Peter, Venom holds them hostage at Horizon High.

A mystery villain puts a bounty on Spider-Man's head, bringing on attacks from Panda-Mania, Hippo and Overdrive.

Anya must step up and embrace being the Spider-Girl; Spider-Man is lured into Mysterio's funhouse and learns that there is a bounty on his head.

Spider-Man faces off against his most bizarre bad guy yet, Jack O'Lantern; he turns Prowler, a reluctant villain, to the side of heroes when he helps him save his brother.

Spidey tracks the identity of the mysterious boss that put a price on his head and who has been sending villains after him.

Spider-Man and Miles Morales discover Doc Ock, whose mind has been hiding inside the metal body of the Living Brain, has been behind the mysterious bounty for Spider-Man’s head.

Spider-Man must fight his way through the Super-Villain Holding Facility to challenge the Living Brain, the robot body that houses the mind of Doctor Octopus.

The Bloodgem accidentally reawakens Gwen Stacy's dormant spider-powers, turning her into Ghost Spider!

Doc Ock intends to bring New York to its knees, but his new brain still contains memories of Uncle Ben.

Doc Ock must adjust to his new life as a hero and is tested by rising crime boss Sand Girl.

Superior Spider-Man is confronted by the Avengers who suspect that he is not who he claims to be.

When Cloak and Dagger emerge to take revenge against Tiberius Stone and his company, Alchemax, Superior Spider-Man must take them down to protect the school.

Superior Spider-Man must face his most challenging opponent when Venom escapes from stasis and attacks Midtown High seeking revenge on Peter Parker.

A series of attacks captures the Avengers one-by-one. Spider-Man is left to figure out who is behind the kidnappings.

Spider-Man takes his mission to The Cellar, where he believes The Regent is using his powers of Cloak & Dagger as well as other supervillains to hold the Avengers captive.

Spider-Man has to take down the slick new villain, Slyde, who is stealing various chemicals from around the city in an effort to create a deadly virus that could wipe out New York.

Spider-Man must team up with Spider-Girl Ghost Spider, and Doc Ock to track down a new threat — the mysterious Goblin Nation.

As Spider-Man and Harry Osborn seek the Goblin King to determine who is behind the Goblin Mask, Spider-Man becomes concerned Harry is leading him into trap.

Peter Parker struggles with the duality of his social life at school and hiding his secret identity from everyone, including his best friend Harry Osborn

Spider-Man, Miles Morales, Spider-Girl, Ghost Spider, Harry Osborn and Doc Ock must stop the Goblin King in his newly acquired Goblin Mech Suit before he destroys New York City.

Peter is accepted into Horizon High: a school for geniuses, where his best friend Harry Osborn was just suspended. Peter makes his debut as Spider-Man and must battle the Vulture.

Spider-Man must work to stop the Scorpion from wreaking havoc at the museum.

Norman Osborn creates the Osborn Academy for Geniuses as a way of saving his son, Harry, the embarrassment of being suspended from Horizon High.

Spider-Man must stop Black Cat from committing a spree of thefts while still keeping his school obligations.

Horizon High throws a dance in honor of Harry being exonerated, but Norman asks Harry to stay at the Oz Academy.

Spider-Man meets the powerful, yet uncontrollable Sandman and helps him reunite with his estranged daughter with the help of the Venom symbiote.

When Spider-Man uses his new black costume, he discovers that there is great danger in his new power; and he must find a way to defeat a costume that wants to destroy him.

After the terror of the symbiote, Spidey is off to the Stark Expo in his old costume. When Ghost hijacks the event, Spidey's only chance to save lives is to unleash the symbiote.

When Miles Morales is bitten by an experimental spider and gains spider powers, Spider-Man must teach him the responsibilities of being a superhero.

Kraven the Hunter does a live broadcast of his hunt for Spider-Man.

On Halloween night, Spider-Man must team up with the incredible Hulk to stop Man-Wolf, a super-strong gamma-powered werewolf, from infecting the rest of Manhattan.

Spidey must stop a low-level villain who has acquired some impressive freezing technology.

The symbiote has escaped the Avengers Compound and attached itself to a new host. Now Spidey must find out how to beat it and who the new person is underneath.

Spider-Man is targeted by a new costumed figure named Screwball for a series of online prank videos which block him from fighting crime.

When Otto Octavius is caught in an explosion that fuses his robot arms to his body, Spider-Man sees the opportunity to recruit "The Octopus" into becoming a hero.

Spidey invites The Octopus to patrol the streets alongside Miles and himself until it becomes clear that Otto isn't exactly a team player.

Peter spends a day at Osborn Academy in the hopes of finding a clue that will convince Harry that his father is out to destroy Spider-Man.

Spider-Man must team up with Gwen Stacy and a reluctant Harry Osborn to investigate the truth behind the missing Raymond Warren aka the Jackal.

Spider-Man tracks a new villain with spider powers who steals his experimental stealth suit and threatens the entire city.

Everyone in Manhattan manifests spider powers; Spider-Man and Spider-Gwen must help Black Widow track down Crossbones before he delivers the vibranium to Arnim Zola and Hydra.

Peter must find a way to cure Gwen Stacy and Norman Osborn after they turn into spider monsters; things get harder when Kraven the Hunter turns New York into his hunting grounds.

Peter and Harry must battle through an island of spider monsters to get to Norman Osborn, who appears to control them all; the boys discover the real mastermind.

To cure the spider-monster population of Manhattan, Spider-Man must lead Kid Arachnid, Anya and Harry on a desperate, last-ditch effort to stop the Jackal.

Spider-Man takes on Doc Ock and his Sinister Five before they brainwash Spidey and destroy New York City.

Spider-Man must find a way to stop Hobgoblin, who seems completely bent on doing whatever it takes to destroy Spider-Man.

Peter Parker is on a field trip to Oscorp when he accidentally gets bitten by a radioactive spider.

Peter uses science to investigate his spider bite.

Peter begins to develop super powers.

Peter predicts his new abilities could bring him fame.

Peter enters a wrestling competition.

With great power comes great responsibility.