A litter of orphaned kittens trail a pair of Dandy Dinmont Terriers. The only girl in a litter of four American Bobtails hunts for her place in the pack. And finally, a naughty Tonkinese kitten proves a handful for her prim and proper mom.

Dexter, a Bulldog who has aspirations to rise above his lazy siblings attempts to prove himself on the agility course. Then, a pack of pups who were rescued from the city streets find themselves in a barnyard full of strange beasts.

A Siamese named Chester tries to find some peace and quiet away from his eight noisy siblings; a British shorthair a cat clinic looks after her six kittens.

In a cozy cabin, a pair of Siberian soul mates’ relationship is put to the test with the birth of their fireball son Calvin. While at a cats only grooming salon, a Turkish Angora kitten named Izzie has to balance her personal style with life in the salon.

At a small farmhouse an adventurous Cairn Terrier named Doogie attempts to befriend a finicky house cat. While a pristine pack of Samoyed pups have to decide whose rules they’d rather follow – their tidy mom or their messy dad.

In the countryside, a German Shepherd mom is training her troop of seven pups to be Search and Rescue dogs. While in the big city an African Pygmy Hedgehog named Prickle is looking for a soft and cuddly companion in a house full of Havanese puppies.

An English Mastiff puppy named Dot searches for a little independence from her tag-a-long sister Olive. And Niles, a Small Munsterlander, tries to live up to his breed’s reputation as top notch hunting dogs, despite the distraction of his fun-loving mom.

In a pack of nine Spinone Italianos, there’s only one thing that keeps a timid pup named Wally calm, his security sock. While a few miles away, a mischievous Pug named Oskar is a constant handful for his orderly librarian mom.

A Siberian Husky has declared himself the leader of a pack of seven pups, but he'll need to back up his bravado with some real sledding smarts. And in a litter of a dozen Irish Red and White Setters, a little runt named Lil has to prove she can keep up.

A pair of Shetland Sheepdogs are concerned that their only pup is getting distracted by the farm’s resident Pomeranian Gino. Plus, in a litter full of tailless Manx, one kitten named Charlie is born with a tail and needs to figure out he fits in.

At an urban animal shelter, a Maltese mix named Coco has a surprise litter, led by bold, only-boy Ralphie - while in the country, a restless Ragdoll kitten named Jolene might be more than her laid-back mom can handle.

In a small town, a dog about town named Izzy brings a rare litter of Portuguese Podengo Pequeno pups into the world, led by go-getter Gisele. Meanwhile, an octuplet of Cockapoos train to be therapy dogs.

The first months of adorable sets of elf cats and Abyssinian kittens are chronicled from their first steps to days of playful contact with new creatures.

Two Bernese Mountain Dog pups bond with their barnyard neighbors. A trio of Shiba Inu girls challenge their spick and span mom with their messy ways. And, in a litter of mixed breed Chatham Hill Retrievers, a young pup takes after his boisterous dad.

A dog spa hostess has her work cut out for her by 10 whippet pups; a mix-breed pup looks to fit in with sisters; mother's serene life is disrupted by a litter of 13 black Russian terriers.

A pup befriends a ferret.

Tabby litter befriends a bearded dragon; Alice the Burmese leads her brothers on an adventure; runt of Siberian litter plays with miniature horse named Kitty.

A Chesapeake Bay Retriever is convinced he's the alpha dog, but his big cousin isn't about to roll over. Miniature Poodle Tater Tot is determined to prove she's the equal of her bigger, louder brothers. And a snowy, fussy Samoyed befriends a Dalmatian.

Litter of Yorkshire Terriers mess around with Guinea hens; Pippa deals with four new siblings; German Shepherd and Labrador Retriever train to be seeing-eye dogs.

Turkish Van needs help from a dog to keep her kittens in check; six European Burmese have loud voices in musical home; pair of Persians raise trio.

A Rat Terrier pup troes to find his place on a ranch full of rambunctious siblings. A stylish Briard named Fresco has to learn to take care of her 10 supersized pups. And finally, a Japanese Chin named Carly tries to spin her way into the spotlight.

A Bullmastiff puppy sticks to his aunt's side as he tries to follow in her footsteps and become a guard dog. A pair of Lowchen pups seek out additional family members. And, an Old English Sheepdog finds himself being herded by tiny sister.

One dozen goldendoodles take over a home and a pet pig's bed; a Westie chases after her wandering twin brother; Swiss mountain puppies find their stride.

A foursome of Neo-Mastiffs have big paws to fill if they're going to be be guard dogs like their Mom. A shy Chihuahua puppy learns that her tiny family have big hearts. And a litter of seven English Setters compete for first place.

Irish terriers meet their bothersome teenage brother. 8 Corgis help on the farm, and an Akita puppy finds her place among her brothers.

Spotted Bengal kittens are bowled over by a lumbering Newfoundland. 4 fluffy Norwegian Forest Cats dip their toes in the surf at their neighborhood beach, and, at a rescue home, 2 kittens find their way into the den mother's heart.

Catch up 1 year later with German Shepherd, French Bulldog and Mini Australian Shepherd puppies.

Poodles, Basset Hounds and Bull Terrier puppies are featured.

Catching up with litters of Portuguese water dog, Rhodesian ridge-back and dachshund puppies after one year.

In a litter of six Maine Coon kitties, only boy Maurice struggles to fit in with his sisters. A quiet kitten with a limp tries to find his voice in a litter of super-chatty Siamese cats. And a shy black kitten tries to befriend an older butterscotch tabby

Catching up with litters of Persian, Bengal and British shorthair kittens after one year.

A shy Papillon puppy named Kitty comes out of her shell with the help of her siblings. A trio of St Bernard puppies follow their noses to big adventures. And finally, an Airedale Terrier named Merlin tries to disappear from her eight brothers and sisters.

A black-and-white kitten plays with its adopted brother, a baby skunk; an orange tabby kitten tries to befriend a canine housemate; a Savannah kitten seeks a playmate.

Four tiny Tibetan Spaniels - all boys - are born into a family of watchdogs. A extra large litter of Newfoundland puppies take to the water as they train to be rescue dogs. And a patchwork puppy tries to blend into a family of Retriever Mixes.

A bear cub befriends a lonely German Shepherd. A deer and a kangaroo have their world turned upside down by a mischievous lemur. And a pygmy goat has a hard time fitting in until he meets a shy puppy. Note: 30 min episode/special

A baby Baboon is taken under the wing of a Golden Retriever. A Teacup Pig and a Flemish Rabbit sneak away from their day jobs and get into trouble. And an adventurous goat and a timid lamb break out of their everyday routine. Note: 30 min episode/special

Star-struck Snow is a Great Pyrenees puppy who dreams of following in her movie star mom's paw prints. A pair of Border Collie pups will need to be brave if they're going to be champion herders. And a Scottish Terrier tries to win over the resident cat.

Six fluffy Coton de Tulear puppies explore their farm home as one of them, Snowflake, struggles to find its place in the world until it meets Pipsqueak, an awkward baby pygmy goat; a mischievous German shepherd puppy struggles in obedience class.

Oreo, a tiny tuxedo kitten meets a similarly attired companion: Nellie the Skunk. Sputnik leads his Russian Blue siblings on a grand adventure. And, Ocicat Freckles tries to keep control of her five mini jungle cats.

Nanook, a shy Chinook, is the only boy in a litter of four, training to be a sled dog. Rocky, the Labradoodle, and his brother Stanley grow up poolside. And Rollo and Pickles are wiener dogs who aspire to be athletes like their mom, a champion hotdog.

A shy Cavalier King Charles Spaniel is coaxed out of her shell by her peppy aunt. Then, everyone wants to be top dog in the Alaskan Malamute home. Finally, three Dalmatians grow into their spots as they show off their skills at the local fire station.

In this "Best of" episode, viewers get a glimpse of the most adorable inter-species animal friendships. From roly-poly Ragdoll kittens and their German Shepherd playmate, to mini-Australian Shepherds and their quacking duckling pals, it's an extravaganza of cute.

Pit bull puppy Thor discovers an urban paradise where it can be free; Collie pup Little Magic must learn to keep up with its pack mates; Chinese Crested puppies Bella and Buttons, though opposite in appearance, team up against a strange new creature.

Toyger kitten Tonya overcomes her shy nature to befriend a large housemate. British Shorthair kittens audition for the role of "greeter" at a vet's office. And fluffy Ragamuffin Otto keep household chores at bay.

Raisin, a wrinkled Shar Pei, guards his toys from siblings Peaches and Pancake. Scout, a brave young Cairn Terrier, attempts an adventure all on his own. And Peanut, the smallest of a litter of Boxers, is steered to glory by his grandfather.

Five little piggies must befriend Penny the Spaniel and learn their new farm home; Clover, a mini-lop rabbit must assert herself with feisty brother Harley; Samson and Delilah teach their hoglet Pip and her spiky siblings about the great outdoors.

Calico kittens mingle with canine clientele at a dog-grooming salon where their mother works. Exotic Shorthair kittens are born into the lap of luxury, but soon reveal their mischievous side. And a pair of Tabby kittens explore the great outdoors.

Godiva Kiss, a Birman beauty queen, is raising three kittens who may follow in her royal footsteps. Tofu, a Cornish Rex kitten, and his siblings befriend Donna the Iguana. Cutie, a tortoiseshell cat is raising twin brothers that are nothing alike.

An adorable showdown takes place between Pucci the Chihuahua and the new Royal Himalayan kittens. Singapura mom Jasmine has a hard time keeping up with her tiny, energetic brood. Short-legged and long legged munchkin siblings navigate the world.

Puck, a keeshond pup, befriends a flock of ducks on the farm while sister Tulip explores the woodshop. A little Great Dane named Marvin is adjusting to his fast-growing body. Cocker Spaniel pups look the same but certainly don't act the same.

Lab mix rescue pup Sally is never seen far behind brother Safari, Pomeranian triplets Sparrow, Wren and Finch carry on mom Star and dad Tucker's job of watching over a feathered menagerie and Ibizan Hound puppies Carmen, Figaro and Arabella try to out chase each other.

Anya the Doberman pinscher and her human best friend, toddler Kaylee, have a big job keeping up with Anya's 12 new puppies. Runt beagle pup Roo hopes his nose will help him hunt with his sisters. Show dog Bichon Frise Angel breeds her champion brood.

In this best-of episode: Bold little Maine coon kitten Lulu tries to help her dad get along with her siblings. Persian kittens prepare to be like their show cat mom, Truly Elegant. Siberian twins Mittens and Socks are rescued from the closet by Maksim, the cat of the house.

Kitten owners go to great measures to take care of their fiercely independent pets as the birth and first few months of three separate kitten litters are documented in order to record all of the important moments in the kittens' lives.

The birth and first months of three different litters of puppies are followed; fawning owners do everything they can to accommodate their new pets; adorable moments of puppies' lives are shown as they eat, sleep and play.

Three delightful litters of puppies come of age; the first few months of Pugs', Mini-Australian Shepherds' and Rottweilers' lives are full of adventure, including an introduction to an agility course and lessons in duck-herding.

Featured are the epic adventures that take place during the first few months in the lives of Savannah, Siberian and Shorthaired kittens; cats grow up in a house full of guinea pigs, turtles and mice and run off to discover surprising, new territory.

The epic stories of three litters of kittens are followed as they grow from helpless "furballs" into rambunctious, young cats; hairless Sphynxes redine "cute"; Burmese cats explore new heights; tiny Ragdolls befriend German Shepherds.

Three litters of kittens pounce throughout the first few months of their lives; beautiful American Curl kittens get ready for life on the catwalk; a set of Tonkinese run circles around their mother; a Maine Coon shows his siblings who is boss.

Three litters of puppies go from cute to cuter during the first few months of their lives; a trio of Rhodesian Ridgebacks runs circles around their mom; fluffy Chow Chow puppies have heaps of attitude; a Havanese has her paws full with five puppies.

The coming-of-age stories of three litters are featured: three sweet puppies keep their Jack Russell Terrier mother active; a Portuguese Water Dog finds out that her litter may not be too fond of water; a Bullmastiff mother's four puppies keep growing.