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Roughhousing daimyo Tokugawa Yoshimune of Kishu reluctantly becomes the Shogun so that he may bring prosperity to everyone in the country. On his procession to Edo Palace, he runs into a little girl begging for a pardon for her father on death row, and his old friend Tatsugoro. To investigate the little girl's story, Yoshimune decides to sneak out of Edo Palace and do a little detective work.

Ogyu Shosen is called a quack doctor, but Yoshimune thinks he should be made surgeon-general.

Hatamoto firemen are causing a nuisance and thieving in town, so fiery Tatsugoro and his gang of construction workers aim to take them down.

A hatamoto's spoiled brat daughter is in the habit of thieving and blaming it on commoners. Meanwhile, Yoshimune becomes preternaturally obsessed with a den-den taiko (a type of child's toy).

Yoshimune's old friend from Kishu, a female lumberjack, comes to Edo to engage in lumber trade, but gets in trouble.

Yoshimune's old friends from Kishu, Sakichi and Onatsu of the lumber store, are leaving town, so Yoshimune comes to bring them a present. He ends up getting in the way of a drug bust and is mistaken for a drug dealer.

Fireman Genzo wins the lottery, but is then reported to the police for having a forged ticket.

Even though he has been made surgeon-general, nobody trusts Ogawa Shosen or Yoshimune's city hospital. Yoshimune decides to get himself admitted as Shin-san to investigate from within.

Satsuma domain bully a store that is in their debt by trying to steal its young master's girlfriend and by framing them for theft. Only a man of stone can save Tamba-ya from destruction!

Yoshimune really wants to attend a festival in Edo, but he has important business to attend to in the palace. Jii says he can go out as long as he is back by 4 PM. This doesn't seem likely, since Yoshimune gets involved in a big fistfight and village drama.

Tatsugoro's family is indebted to a samurai family, so Tatsugoro gives the samurai family his very best fireman to adopt, since the samurai have no heir of their own. The other samurai do not like him.

Ryuko and Isonokaze were sumo wrestlers for a clan who tried to make them throw a match. Ryuko hides out at the fire house and meets Shin-san, who is very excitable (maybe he ate a lot of sugar) and really wants to wrestle him. Eventually Shin-san learns of the wrestling drama that is unfolding...

A certain han ruled by a child lord is having money trouble, so one of the han's samurai starts a sweet bean soup restaurant, but he has some trouble getting customers...

A land reclamation project is taking place largely with Shogunate funds, carried out by contract with 2 companies (which are marrying their kids together as the ultimate symbol of the contract). One of the companies invents a bomb with a long fuse, to blow up a mountainous area in the reclamation zone. The other company decides to assassinate the first company, and steals the bomb...

Osono's dad Seiemon comes to town. He is now a cotton-farming country samurai. Needs dried sardines for fertilizer. The hatamoto of sardineland is driving the fishermens' prices down and forcing them to sell to 1 store so all the farmers secretly sell to Seiemon. The merchant tries to assassinate Seiemon and fails, since Seiemon is a ninja. Seiemon stays at the firehouse and plans to secretly assassinate the criminals, then kill himself, because he's depressed.

A man makes little pretty sugar candies for kids and tells funny stories. He used to be a counterfeiter because of his great manual dexterity, but vowed to turn his life around. Shin-san becomes "interested" in him (bastard we know you just want free candy) just when the guy's old friends force him to counterfeit again...

Edo is invigorated by an unusually aggressive and outspoken female doctor, Oshino, who physically beats her patients if they do not obey her.

A bad gang leader kidnaps Tadasuke's wife (who never appeared before or since), as she went to the shrine to pray for a baby. Tadasuke decides that justice outweighs his bride and prepares to prosecute the gang leader anyway, so Shin-san lets the prisoner go secretly to try and follow him to Tadasuke's bride...

Clannish sake sellers turn against a travelling Osakan female sake seller to force her out of the market; only her long-lost son, an Edoite sake seller, can save her.

Oshino, the female doctor with a fist, is in charge of a temple that gives free medical service to orphans, but it is reputed that she is stealing all the money instead.

Shoheiko, the official Shogunate college, has an admissions scandal where the bureaucrats turn out to have been accepting bribes for admissions. Yoshimune suggests opening it to commoners and calls up some obscure scholars; the vicious bureaucrats attack and kill one. Shin-san absolutely loses his mind, but Tatsugoro is there to give him a helping hand.

Ryuko's friend is killed by a rice wholesaler. Shin-san investigates this and discovers a whole sordid rice-based drama, including collective punishment, famine, and assassination.

An unbalanced ronin wants to become the sword teacher to a daimyo, so he can get enough money to buy back his really sexy sword from the pawn shop. However, a competitor attacks him, crippling the ronin's hand. Shin-san is really mad about this, even though the ronin attacked him earlier.

A pregnant safflower farmer's husband is run over by the local lord's horse. She's lured to the daikan's office to get compensated but is raped and turned into the lord's concubine instead. She schemes to have herself murdered so Ooka Echizen will enter the manor and discover these great crimes.

A kind but untalented kitchen-supervisor samurai is assigned to accompany his domain's gift to the Shogun: big blocks of ice. Shin-san, tramping around Shinjuku, accidentally discovers this delivery and starts accompanying it too, and discovers a rival domain is trying to kill the ice to humiliate the first domain.

A mysterious illness (beriberi) becomes common and Yoshimune calls his doctor to find out what the cause is. His doctor says only his own special blend of medicine (very expensive) can cure it. Oshino, the female doctor with a fist, however, believes the solution is more simple (and involves punching people).

Kano Gorozaemon, who is practically Yoshimune's adoptive father, goes out into Edo to get a surprise present for the Shogun, and is kidnapped by a nutter who wants to frame him for murder to steal his job.

A lord lets 3 master ghost actresses into his house as maids, somehow doesn't connect this with supernatural happenings in his house.

Kikue, the daughter of a potter. comes to Edo and meets her old friend Shin-san, who she recognizes as the Shogun. She came to marry Kano Gorozaemon, who proposed to her when she was eight (??!) but Kano backed out.

The Ogobanshu (kind of like a guild of hatamotos) want to hunt, but in setting the borders of the hunting area they recklessly steal the corner of a VERY sensitive farmer's farm.

Matsumae domain official and ebisu-ya are conspiring to give predatory loans to alcohol shops. Lady merchant Omasa from Osaka wants to get a better deal, and her son unfortunately took the debt from his main sake supplier, so now she needs to get money to save both their skins.

Hatamotos, a domain, a runaway killer samurai from the domain, the firemen, and jii for some reason, all end up in a gigantic free for all fight.

Shin-san accidentally gets involved with two low-class thieving morons, to Tatsugoro's horror. Tatsugoro finally manages to get rid of them, and one of them is promptly killed by evil ninjas for having seen something he should not have. Yoshimune learns they were raising a bunch of orphans in an awful shack with their scammed money, and decides he must avenge the dead criminal.