Illusionist Derren Brown starts by exploring the world of a Liverpool-based psychic medium. Joe Power claims he can communicate with the dead, and alleges that one of the many people he has made contact with is John Lennon.

Derren investigates the Bronnikov method, which claims it enables people to see without using their eyes. He travels to Holland with a woman who has been blind since 1995 to test the method's plausibility.

Derren investigates the world of Lou Gentile, a top American ghost hunter who for the last 20 years has been helping the haunted and possessed of America.