Featured performances and roasts by Jim Breuer, Mario Cantone, Lenny Clarke, Doctor Dre, Dane Cook, Nick DiPaolo, Adam Ferrara, Michael J. Fox, Peter Gallagher, Don Gavin, Gina Gershon, Gilbert Gottfried as Denis' Irish Wolfhound, Ed Lover, Joe Mantegna, Conan O'Brien, Colin Quinn, Rene Russo, and Christopher Walken.

Jeff Foxworthy was roasted by Nick DiPaolo, Lisa Lampanelli, Greg Giraldo, Colin Quinn, Denis Leary, Jay Mohr, Steve Bridges as U.S. President George W. Bush, Christian Finnegan, Gilbert Gottfried as Jeff's cow, Heidi Klum, Patrice O'Neal, Anna Nicole Smith, and G. E. Smith. The hip-hop group B.A.M.A. also performed their cover of "Sweet Home Alabama"

Pamela Anderson was roasted by Courtney Love, Adam Carolla, Bea Arthur, Nick DiPaolo, Greg Giraldo, Elon Gold, Eddie Griffin, Lady Bunny, Lisa Lampanelli, Tommy Lee, Jeff Ross, Sarah Silverman, Andy Dick, roastmaster Jimmy Kimmel and pre-taped appearances by David Spade and Hugh Hefner. This roast featured a large amount of jokes and satire regarding sex directed from roasters toward fellow roasters, complete with Andy Dick appearing as Pamela's plastic surgeon and groping her breasts as part of his skit. Many of the jokes were also directed at Courtney Love for appearing to be inebriated (but claiming to have been sober for a year), Bea Arthur's masculinity, Andy Dick's ambiguous sexuality and Lisa Lampanelli's full figured body as well as her attraction towards black people. One of the audience members was Anna Nicole Smith.

William Shatner roast was Executive Produced by Joel Gallen, with Aaron Matthew Lee serving as Head Writer. Jason Alexander acted as roast master with Andy Dick (as the "love child" of James T. Kirk and Spock), Farrah Fawcett, Greg Giraldo, Lisa Lampanelli, Artie Lange, Nichelle Nichols, Patton Oswalt, Kevin Pollak, Jeff Ross, George Takei, Betty White, and Fred Willard performing the roasting duties. Special, pre-taped, guest appearances were made by Leonard Nimoy, Sandra Bullock, Ben Stiller, Sarah Silverman, Jimmy Kimmel, and Clint Howard. The Leonard Nimoy sequence which originally opened the broadcast on Comedy Central (Nimoy and Shatner were shown having an argument over the phone) was omitted from the DVD release, while many pre-taped sequences and jokes told during the roast itself were added back in after originally being cut.

The roasters were Ice-T, Jimmy Kimmel, Snoop Dogg, Greg Giraldo, Patton Oswalt, Lisa Lampanelli, Jeff Ross, Carrot Top, Sommore, and Brigitte Nielsen. Celebrities such as the cast of Flavor of Love, Ron Jeremy, comedian Luenell, comedian Red Grant, Scott Adsit from 30 Rock, Nicole "Coco" Austin, Kordell Stewart, Derek Parker, Moonlite BunnyRanch owner Dennis Hof, and Chyna were in the audience.

Saget's Full House co-star John Stamos was the roastmaster. The roast included Susie Essman, Greg Giraldo, Brian Posehn, Jim Norton, Jeff Garlin as fictional Full House executive producer Saul Schwartz (though he broke character at the end), Gilbert Gottfried, Jon Lovitz, Norm Macdonald, Cloris Leachman, and Jeff Ross.[8] Pre-taped appearances were delivered by Sarah Silverman, Lewis Black, and Don Rickles. Full House co-stars Lori Loughlin, Jodie Sweetin, and Dave Coulier were shown in the audience along with Growing Pains star Alan Thicke, Rex Lee of Entourage and Quantum Leap & Star Trek: Enterprise star Scott Bakula throughout the roast. Alonzo Bodden was also in the audience. Artie Lange was scheduled but did not show at the roast because he had entered a rehabilitation center.

The Comedy Central Roast of Larry the Cable Guy was taped on March 1, 2009.[11] This marks the first time that a previous roastmaster has become a roastee. On February 12, 2009, the roasters were announced to include Nick DiPaolo, Jeff Foxworthy, Greg Giraldo, Toby Keith, Jeffrey Ross, Reno Collier, Maureen McCormick, Warren Sapp, and Gary Busey. Bill Engvall made a pre-taped appearance.

The Comedy Central Roast of Joan Rivers was taped on July 26, 2009.[12] The roasters included Carl Reiner, Gilbert Gottfried, Mario Cantone, Whitney Cummings, Tom Arnold, Brad Garrett, Robin Quivers, Greg Giraldo, and Jeff Ross. Donald Trump and Don Rickles made a pre-taped appearance and Melissa Rivers came from the audience to roast her mother. Other audience members included Michael C. Hall, Jennifer Carpenter, Alan Thicke, TJ Miller, Chris Pratt and Anna Faris.

Roasters included Jeff Ross, Pamela Anderson, Lisa Lampanelli, Hulk Hogan, Jerry Springer,[14] Whitney Cummings, Greg Giraldo, George Hamilton,[15] and Gilbert Gottfried, Sharon Osbourne and Piers Morgan made pre-taped appearances, and William Daniels reprised his role as the voice of KITT. Seth MacFarlane was the roast master and was his first appearance on the show. The audience included John Slattery, Craig Robinson, Christina Milian, Hasselhoff's two daughters, Hayley and Taylor, Hulk Hogan's son, Nick, and fellow Baywatch alumni Alexandra Paul, Nicole Eggert, Gena Lee Nolin, Traci Bingham, Angelica Bridges and Jeremy Jackson. To close the show, Hasselhoff sang "This Is The Moment" from the musical Jekyll & Hyde, which he formerly starred in.[16] This was also the final roast in which Greg Giraldo participated. Giraldo died on September 29, 2010.

The Comedy Central Roast of Donald Trump was originally taped on March 9, 2011.[18] Roasters included Whitney Cummings, Lisa Lampanelli, Jeffrey Ross, Marlee Matlin (interpreted by friend and business partner Jack Jason, and later a surprisingly appereance by Gilbert Gottfried), Anthony Jeselnik, Larry King, Snoop Dogg, and Mike "The Situation" Sorrentino.[19] Melania Trump, Ivanka Trump, Ice-T, Russell Simmons, John Legend, Lindsay Lohan, and David Foster were in the audience. The roast consisted of jokes toward Trump's hairstyle, his show The Apprentice, and his family. Jokes were also made about Jeselnik's fame (or lack thereof), Matlin's deafness, King's age, and Jersey Shore. Several roasters paid respect to Greg Giraldo, a Comedy Central Roast regular, who died on September 29, 2010. Mike "The Situation" Sorrentino was highly criticized for his performance; as a result, Comedy Central pulled several of his jokes from the television airing of the roast.

The roast was taped in Los Angeles on September 10, 2011, and was broadcast on September 19, 2011. Roasters included Mike Tyson, Jeff Ross, Anthony Jeselnik, Steve-O,[22] William Shatner, Kate Walsh, Jon Lovitz, Patrice O'Neal and Amy Schumer. Slash made an appearance playing his guitar during Sheen's entrance. Brooke Mueller, Aaron Paul, Corbin Bernsen, Duane Chapman, Michael Boatman, Kristin Cavallari and Richard Kind appeared in the audience. Seth MacFarlane made his third appearance as the roastmaster. A montage of Sheen's film and television work were featured, though due to legal reasons, clips of his tenure on Two and a Half Men were never used. This was O'Neal's final television appearance before his death on November 29, 2011.

Roasters include Jeff Ross, Tom Arnold, Katey Sagal, Carrie Fisher, Ellen Barkin, Anthony Jeselnik, Seth Green, Amy Schumer, Wayne Brady, and Gilbert Gottfried. Sarah Chalke, Alicia Goranson, and Michael Fishman will be in attendance. Sharon Stone had been announced as one of the roasters, but dropped out for unknown reasons prior to the event.

The multi-hyphenated jack-of-all-trades James Franco finds himself on the receiving end of barbs served up by his friends. Roast Master Seth Rogen leads roasters Aziz Ansari, Bill Hader, Jonah Hill, Nick Kroll, Natasha Leggero, Jeff Ross, Andy Samberg and Sarah Silverman.

Several roasters, and the master himself Kevin Hart, make fun of Justin Bieber.

Mr. Lowe is skewered about his sex tape, his nanny escapades and his acting career under the oversight of the roast master, David Spade. But it’s Ann Coulter who really feels the heat. Peyton Manning, Jewel, Rob Riggle, Ralph Macchio and Nikki Glaser help do the dirty work.

Traditional comedy 'roast' where celebrities, comics and friends poke fun at actor Bruce Willis.

Sean Hayes serves as roast master as it is Alec Baldwin's turn in the hot seat. Robert De Niro, Jeff Ross, and Caitlyn Jenner among others take jabs at the actor/comedian.