When 31-year-old real estate appraiser Mike Williams mysteriously vanishes while duck hunting in the Florida swamps in December of 2000, authorities suspect he accidentally drowned. For sixteen years Mike’s disappearance remains a mystery. The case heats up when police receive a distress call from the victim’s wife in 2016. Featuring interviews with detectives and the victim’s mother as well as rare footage of the crime scene and recorded audio confessions with the accused, the episode explores how the disappearance unfolded into a sinister plot to cash in on millions of dollars of life insurance.

Easter Sunday of 1992, the body of missing woman Lisa Ziegert is found in a field. The investigation yields hundreds of leads but no true suspect. After more than two decades on ice, the case is revived when DNA phenotyping puts a face to the killer.

Just after the last day of school in 1984, 15-year-old Reesa Trexler is found murdered in her grandparents' home. For decades, a stalled investigation only fuels the town rumor mill, pointing an accusing finger at Reesa's 13-year-old sister, Jodie.

When a beloved schoolteacher is found murdered in her Neptune, New Jersey apartment in the fall of 2009, suspicion is cast on her soon to be ex-husband. Long after the case goes cold, a detective embarks on a mission to help the man clear his name and track down the real killers.

In August 1972, the body of Jody Loomis is found in the woods. 34 years later, the killer's DNA is recovered from Jody's old clothing but it isn't matched until 2018, when genetic genealogy helps point to one suspect--whose guilt must be proven in court.

On February 2, 2010, two masked gunmen commit a violent robbery and shoot Michael Temple Jr., rendering him a quadriplegic for five years before his death. In this unusual cold case, DNA from a knife is used to create a sketch of the killer.

13 days after Pam Pitts disappears in 1988 her charred body is found at a popular hangout spot in the Arizona desert. When a second victim is discovered in a mineshaft, detectives suspect the killer may have known them both, but the truth is decades away.

In late 1983, the bodies of five people abducted from a local fast food restaurant are found brutally murdered in an oil field. The main suspect is long believed to be a well-connected local man, until new evidence reveals the true killers.

When 23-year-old Tonya McKinley is found brutally murdered on New Years Day 1985, a little boy is left motherless. A family must wait 35 years for advancements in forensic science to finally catch a killer using familial DNA.